Which of the following is a symptom of Prader-Willi syndrome?

Which of the following is a symptom of Prader-Willi syndrome?

• A. Amenorrhea, undescended testes
• B. Tall stature
• C. Hyperactivity only at night
• D. Regular puberty timing

Answer: (A)

Hypogonadism is a key feature of Prader-Willi syndrome, leading to reduced sexual development and issues like amenorrhea in females and undescended testes in males. This makes the combination of amenorrhea and undescended testes the best match because it directly reflects the impaired gonadal function common in Prader-Willi. Other descriptions don’t align as well: individuals with Prader-Willi typically have short stature rather than tall, hyperactivity is common but not limited to nighttime, and puberty is often delayed or incomplete rather than regular.

Hypogonadism is a key feature of Prader-Willi syndrome, leading to reduced sexual development and issues like amenorrhea in females and undescended testes in males. This makes the combination of amenorrhea and undescended testes the best match because it directly reflects the impaired gonadal function common in Prader-Willi. Other descriptions don’t align as well: individuals with Prader-Willi typically have short stature rather than tall, hyperactivity is common but not limited to nighttime, and puberty is often delayed or incomplete rather than regular.